Ответ:

(4⁻⁶ · 16⁻⁵) / 8⁻¹⁰ = (2²)⁻⁶ · (2⁴)⁻⁵ / (2³)⁻¹⁰ = 2⁻¹² · 2⁻²⁰ / 2⁻³⁰ = 2⁻¹²⁻²⁰ / 2⁻³⁰ = 2⁻³² / 2⁻³⁰ = 2⁻³²⁻⁽⁻³⁰⁾ = 2⁻³²⁺³⁰ = 2⁻² = 1/4