\[4(a - 3b) - 3(2a + b) =\]
\[= 4a - 12b - 6a - 3b =\]
\[= - 2a - 15b;\]
\[a = 2;\ \ b = - 4:\]
\[- 2 \cdot 2 - 15 \cdot ( - 4) =\]
\[= - 4 + 60 = 56.\]