**Решение:**
1) 16,53 + (-19,8 + 2,19) = 16,53 + (-17,61) = 16,53 - 17,61 = -1,08
2) (-2 \frac{2}{3} + (-5 \frac{1}{4})) + 3 \frac{3}{5} = (-2 \frac{2}{3} - 5 \frac{1}{4}) + 3 \frac{3}{5} = -(2 \frac{2}{3} + 5 \frac{1}{4}) + 3 \frac{3}{5} = -(2 \frac{8}{12} + 5 \frac{3}{12}) + 3 \frac{3}{5} = -7 \frac{11}{12} + 3 \frac{3}{5} = -7 \frac{55}{60} + 3 \frac{36}{60} = -(7 \frac{55}{60} - 3 \frac{36}{60}) = -(4 \frac{19}{60}) = -4 \frac{19}{60}
3) (-15,27 + 12,1) + (19,97 + (-16,8)) = (-15,27 + 12,1) + (19,97 - 16,8) = -3,17 + 3,17 = 0
**Ответы:**
1) -1,08
2) -4 \frac{19}{60}
3) 0