1) $$2a^3 \cdot (-5a^4b^5)^2 = 2a^3 \cdot (-5)^2 \cdot (a^4)^2 \cdot (b^5)^2 = 2a^3 \cdot 25 \cdot a^{4\cdot 2} \cdot b^{5\cdot 2} = 50a^3a^8b^{10} = 50a^{3+8}b^{10} = 50a^{11}b^{10}$$
Ответ: $$50a^{11}b^{10}$$