Ответ:

Преобразуем смешанные числа:

\(6\frac{1}{3}=\frac{19}{3}\), \(4\frac{5}{9}=\frac{41}{9}\), \(2\frac{1}{21}=\frac{43}{21}\).

\(\frac{19}{3}-\frac{41}{9}=\frac{57}{9}-\frac{41}{9}=\frac{16}{9}\).

\(\frac{3}{7}+\frac{43}{21}=\frac{9}{21}+\frac{43}{21}=\frac{52}{21}\).

\(\frac{16}{9}\cdot\frac{52}{21}=\frac{832}{189}=4\frac{76}{189}\).

Ответ: \(4\frac{76}{189}\).